SARS cov2 and Covid 19


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  • #64202
    N_

      Deaths “with Covid19” per 1m population so far:

      US, Britain, Italy, Sweden, France: ~1000
      Germany, Russia: ~400
      China: 3
      Taiwan: 0.3

      (Source.)

      #64209
      ET

        Pulmatrix Appoints Respiratory and Allergy Expert,Michael Yeadon, PhD, to Scientific Advisory Board.
        https://www.pulmatrix.com/news/Pulmatrix_100711.pdf

        Pulmatrix Demonstrates Superiority of iSPERSE in Delivering An Effective Multi-Drug Inhaled Dose Compared to Conventional Formulation…..
        https://www.pulmatrix.com/news/Pulmatrix_103111.pdf

        “As a drug discoverer, I am aware of a number of areas of target-rich biological processes for which drugs could be invented, which may not easily fit into the existing inhalation drug-delivery technologies. Rather than discard such candidates, or worse, the targets themselves, I’d recommend innovators take a close look at iSPERSE. If this becomes proven in clinic, it could become the new gold standard”.”

        PULMATRiX is committed to the development and commercialization of novel and transformational medicines for patients all over the world, using our proprietary iSPERSE™ technology to optimally deliver both respiratory and non-respiratory therapies via the respiratory system.

        Covid anti inflammatory drug delivery maybe?

        #64210
        ET

          And a little more:

          https://biopharmajournal.com/2020/11/04/pulmatrix-inc-nasdaqpulm-and-its-partner-sensory-cloud-announce-fends-commercial-rollout/

          “Pulmatrix Inc (NASDAQ:PULM) And Its Partner Sensory Cloud Announce FEND’s Commercial Rollout”

          ” that FEND’s commercial launch is an important milestone for his company because it will help to combat the coronavirus pandemic more effectively.”

          A pandemic their Respiratory and Allergy Expert appointed to their Scientific Advisory Board states isn’t happening….?

          ” They are optimistic that FEND will not only help to reduce the spread of the coronavirus but that it will help to make a notable impact in fighting against the pandemic at a global scale. Pulmatrix also expects to receive royalties from Sensory Cloud as part of their distribution agreement.”

          What’s going on?

          #64211
          N_

            Some will doubtless “think” it’s a case of “They’re only dropping peppermints and daisy-chains.”

            In context:

            I smell something burning. Hope it’s just my brains.
            They’re only dropping peppermints and daisy-chains.

            How important might Pulmatrix be, ET? It’s not hard to imagine a squirt up the schnozzer job getting official backing…

            Sniffing isopropanol after one has washed one’s hands in it is very sensible.
            (The idea is to whack viruses that infect when inhaled – some people need reminding.)
            It sometimes gets me some funny looks in Tesco, though!

            #64212
            N_

              FEND is just calcium chloride plus kitchen salt (sodium chloride), right?
              Then there are neti pots.

              #64219
              ET

                “How important might Pulmatrix be, ET?”

                I dunno N_, they are listed on NASDAQ but their share price has plummeted since their early days. However, a treatment that prevents shedding of virus or a drug delivery system directly to lung cells of an anti-inflammatory agent and a ready market, who knows how that might change.

                #64220
                ET

                  FEND not only reduces 99% of the particles passing through the nasal cavity but it also filters 75% of the particles being exhaled. Researchers also believe that FEND might increase the effectiveness of wearing surgical masks, especially in indoor situations.

                  From the link to FEND from earlier post.

                  #64223
                  Clark

                    Michael Yeadon, death-dealing, manipulative spiv. Good digging ET.

                    Conspiracy theorists, note how you were manipulated: Yeadon:

                    – “For reasons I don’t understand, given the significance of what I’m about to tell you, none of the so-called medical correspondents and science journalists on radio and TV have ever (as far as I know) spoken of the four, endemic, common-cold inducing coronaviruses.

                    All he had to do was tell you that SAGE are liars whereas he was imparting knowledge the “MSM” were keeping from you, and you fell for it. And he actually encouraged you to spread deadly infection so his company could make more profit.

                    I don’t have a word for filth like Yeadon.

                    • This reply was modified 3 years, 4 months ago by modbot.
                    #64224
                    Clark

                      N_, January 3, 19:23 – “Meanwhile in Wuhan in China people are allowed to socialise now as much as they like”

                      Of course, because infection prevalence there is now very low. But they’ll only be able to get a bus to their socialising if their QR code shows them as uninfected; Track and Trace. That’s what it could have been like here by now if we had a half decent government.

                      #64225
                      Clark

                        Manaus, Brazil, had a very hard first wave. Seroprevalence surveys indicated at least 44% had antibodies and extrapolation suggested 76%, which means that Manaus should have achieved herd immunity.

                        But Manaus is having a second wave, and it has already made more people seriously ill than the first.

                        Node, take good note.

                        #64226
                        Clark

                          Zambia’s second wave looks like another example like Manaus.

                          #64227
                          Clark

                            Dave, January 3, 10:24 –

                            “New Zealand […] put in travel restrictions almost before COVID-19 was officially known about, but any delay in the spread of a virus […] ends once the restrictions are lifted, even if they work anyway.”

                            See the article SA linked for you; restrictions were mostly lifted on May 14. And they had worked, in New Zealand’s winter; New Zealand had 2,181 cases and 25 deaths. New Zealand has wiped out covid-19 twice.

                            #64228
                            Clark
                              #64230
                              ET

                                I am going to paint a disturbing picture with my next comment. I have said that where I live what was done was pretty much what New Zealand did and because of that we here are in a good position. No social distancing, everything open, no masks etc etc
                                Disturbingly, we have had two people test positive after they had isolated for 14 days.

                                “What made these positive results unusual was they came after the two individuals had completed a fourteen day period of isolation…….”

                                I don’t want to draw unnecessary attention to us but these two tested positive on day 21. They had diligently followed the rules here having returned from elsewhere. They were officially told to go about their normal business after 14 days of isolation. So, they not unreasonably did so. The authorities did, in my humble opinion, all what they could be expected to do. They traced, contacted any who might have been contacts etc etc

                                I cannot fault how they went about dealing with this situation here. What is worrying is that perhaps the 14 day isolation period isn’t now enough.

                                “The two individuals who tested positive, arrived here, accompanied by another person, on Thursday the 10 December. All three began the required fourteen day period of self-isolation in shared accommodation. Having displayed no symptoms of the virus, the self-isolation period ended at noon on Wednesday the 23 December and all three individuals were free to go about their business. On Wednesday the 30 December, one of the individuals called the COVID-111 service to report that they had COVID-like symptoms. They were told to self-isolate and were booked in for a test.

                                That test result came back the next day – New Year’s Eve – and was found to be positive. The individual was required to self-isolate and the contact tracing process began. Eight close contacts were initially identified.”

                                That was 7 days after the end of the self isolation period which is not broken here, unless you have a jet ski.

                                This is a worrying development. If this virus remains transmissible beyond the currently advised isolation period, perhaps because of the new variant then we are in for hurt. We don’t know this yet but I’ll keep you posted.

                                #64235
                                N_

                                  When you thought Britain couldn’t get any crazier: from the Torygraph: “Exclusive: Sir Geoffrey Boycott voices fears over delays to second dose of Pfizer jab.

                                  Woman-beater Geoff Boycott is a darling of many right-wing British media consumers, along with Enoch Powell and Vera Lynn.

                                  The headline obeys the first rule of advertising: show (or in this case, mention) the product. “Pfizer, Pfizer, lovely helpy Pfizer. Naughty ol’ government for not helping Pfizer even more. Pfizer, Pfizer! What’s good for Pfizer is good for all cricket fans, and for all ‘Britons’ generally, especially white ones who own their own properties!”

                                  Never forget that Big Pharma spends far more on influencing minds than it does on research, development, and production all added together.

                                  How’s the bank balance, Geoff?

                                  #64236
                                  N_

                                    “Geoff Boycott” is a masterfully managed brand… You can almost hear him say “I speak my mind. Always have done. The government should get a bloody move on!”

                                    If only “left-wing teachers”, “snowflakes”, “coloured” people, the EU, “trendy journalists and vicars”, “longhaired layabouts”, etc., could be blamed for the government’s hesitation and for politicians’ lack of boldness and poor command skills. Tory scum would be in seventh heaven!

                                    Maybe Geoff Boycott and Marcus Rashford use the same agent?

                                    #64237
                                    ET

                                      Never forget that N_ spends far more time on distracting than N_ does on developing a debate, and answering any countering argument to what he/she says. You are a wall flower N_ with nothing to say.

                                      #64238
                                      ET

                                        Perhaps I am being a little harsh here, you have nothing pertinent to say is what I mean.

                                        #64239
                                        SA

                                          ET
                                          Thanks for that piece of information which is indeed disturbing. Do they know whether the virus was the new variant, or even yet another different one, because prolonged incubation period may also be one of the other effects of a mutation. This subtelety would be missed on the mainland where no such vigilance about self isolation and contact tracing is occurring. Also do you know where these people have been before coming to your paradise island?

                                          #64240
                                          SA

                                            Re:N_
                                            Yes that is his/ her style. I can’t recal getting any answers or engaging in any debates, just musings.

                                            #64241
                                            SA

                                              Another way of course that transmission can occur is through fomites. It is said that this is not a very likely route of transmission but recent cases from China suggest that when contamination of food which is refrigerated or frozen may lead to transmission of virus not only by consumption of food but also by contact and other means. Although this is disputed, the objections seem to come from sources that value trade more than caution on such matters.

                                              “The U.S. Department of Agriculture said it also prodded China on two occasions to match its trade restrictions with an accurate assessment of risk, adding that Beijing’s most recent COVID-19 trade regulations “are not based on science and threaten to disrupt trade.”

                                              https://www.npr.org/sections/goatsandsoda/2020/12/16/946737184/china-has-a-theory-about-its-new-covid-cases-many-scientists-are-skeptical

                                              #64242
                                              SA

                                                Et
                                                This is unusual but not unique as outliers have been described before.

                                                #64253
                                                N_

                                                  @Clark – rather than be consumed with hatred when you read words written by Mike Yeadon, or think about those who circulate them, an emotion which is beneficial neither for yourself nor for the world outside of yourself, maybe forget about the finger pointing at the moon and look at the moon instead?

                                                  He’s right, what he says about there being several species of coronavirus, the common cold-causing ones being relatively harmless, and he’s right that this is rarely if ever being mentioned in the MSM.

                                                  It’s interesting that about half the times I have said to people that the bug that’s going around is a strain of SARS, they respond with fear in their eyes, say I’m a “conspiracy theorist”, and act as if I might infect their minds.

                                                  The reason it’s not generally called “SARS” or “the new strain of SARS” is to do with marketing and propaganda. That is an extremely straightforward observation the truth of which should be obvious to every left wing person.

                                                  It is a sad fact that in the reigning culture people have a HUGE ability to make up idiotic reasons to defend whatever crap they’re spewing out that they got from those above them in the opinion chain and which they have never reflected on, because they don’t reflect on shee-yit and because they respect those who stand above them so much. Generally speaking they respect those who stand in front of microphones, and in Britain those who speak with posh accents. In Britain they even sometimes respect opinion channellers who don’t sound as if they went to private school and who present themselves as “grammar school boy” engineer or manager types, especially if they can flash a charming smile or deliver a straightbacked “expert” schtick even in a non-RP accent. That’s the cultural reality we live in. The stupid idiots.

                                                  I haven’t heard the fact that there are other coronaviruses than SARSCov2, ones that cause about ~15% of cases of the common cold and nothing more serious that that, mentioned in the MSM either. (Most cases of the common cold are caused by rhinoviruses, which belong to a different family, for the record.)

                                                  But I have heard large numbers of people refer to “coronavirus” without a preceding article whether definite or indefinite, as if it were an illness. A virus is not an illness. To point that out is not pedantry. Most people who are infected with SARSCoV2 fight it off with their immune system’s first line of defence, which is to say without “specialised” antibodies coming into action and without even getting any symptoms. That is extremely important. It is being totally ignored (and misdirected from) in all the propaganda which encourages moronic punters, as they copy whatever they’ve been told by those above them in the opinion chain, talking as if they understand about the spread and effects of infectious disease. Washing your hands a lot (even if you don’t sing “God Save the Queen” when doing it, which is what Jacob Rees-Mogg advised last year) using proper bug-killing liquid and trying to cut down the amount of surfaces you touch that other people have touched (to prevent infection by “fomites”) is important. Strengthening your immune system is also important, and if you don’t know anything about how to do it then washing your hands all the time may not do much good. Many of those who have strong immune systems have breathed in SARSCov2 probably in quantities that would have caused serious symptoms in some people, and they don’t even know anything about it. It was just one of the many bugs they breathe in all the time without noticing. Anybody who doesn’t try to eat stuff to strengthen their immune system during a pandemic is an idiot, and it is they who should be treated with contempt, not whatever statement you have read on the internet. Such people don’t only endanger and injure themselves; they also spread the virus that everyone is talking about.

                                                  PS Internet “debate” is a morass, ET. Do you think I would waste time “debating” with those who type one-liners such as “you have nothing pertinent to say”? You would probably not be so rude to my face in real life. Nobody forces you to read anything anybody has written on this disgusting medium called “the internet”. Posters here differ in the amount of investment they put into the “scene” here, just as on any other website that allows all-comers to post. There are those who invest less of themselves than you do, and those who invest more. Relax, my friend, and Happy New Year.

                                                  #64255
                                                  Clark

                                                    ET, thanks; it is indeed very disturbing. We need to know which variant.

                                                    SA, yes; one possibility is that infection could have occurred from one of the travellers luggage during their quarantine period. And yes, similar outliers have been seen from early on. Also, persistence of infection beyond nominal recovery has been detected in intestinal cells and neurons.

                                                    We should NOT underestimate this virus. It keeps surprising us and we have no way of knowing what the next surprise may be. We should do our utmost to eradicate it.

                                                    #64256
                                                    ET

                                                      @SA
                                                      To get here they’d have had to transit via the UK and use either ferry or a small number of flights still operating. It isn’t mentioned whether they were anywhere else before that. There hasn’t been any mention of the virus strain as yet but I am sure they are looking into that and we will hear in time. They have done extensive contact tracing and made public any shops, bars and any other locations where the individual had visited. A number of close contacts are in self isolation but the public message is that the risk is low. Those who were visiting or working in the locations during the relevant times are asked to self-isolate and contact 111 if they develop symptoms of Covid-19.

                                                      @N_

                                                      “PS Internet “debate” is a morass, ET. Do you think I would waste time “debating” with those who type one-liners such as “you have nothing pertinent to say”?”

                                                      Then why bother posting at all? But hey, I’m glad to have provoked a response from you albeit not the first time.

                                                      “You would probably not be so rude to my face in real life…”

                                                      If engaged in conversation where one party to said conversation made no relevant replies, I most definitely would.
                                                      I am sure you do have something to say N_ and being “on topic” and making posts relevant to what others have posted would help to elucidate that.

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